Abstract # 2418 Bladder Filling Status Strongly Influences Target Volume Changes in Post-hysterectomy Patients Treated with Intensity Modulated Radiation Therapy (IMRT) for Gynecologic Cancers

Presenter: Thawani, Nitika

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Adjuvant radiation after hysterectomy for cervical and endometrial cancer is an important treatment modality. Although not without morbidity, toxicity is reduced with the use of IMRT. However, in order to ensure adequate coverage, the PTV margin must account for internal organ motion and target volume changes. The definition of margin is of vital importance as to not underdose the target and decrease local control, or overdose normal tissue and increase toxicity. This study was undertaken to determine the change in the posthysterectomy target volume with bladder filling status.

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