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Abstract # 3044 Differences in Dose-volumetric Data between Heterogeneity Correction Algorithms for Stereotactic Body Radiation Therapy for Lung Cancer: Is there Any Impact of the Algorithms on Local Control?

Presenter: Matsuo, Yukinori

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Materials/Methods:
Fifty-four patients who underwent SBRT for primary lung cancer with 48 Gy in 4 fractions at the isocenter during September 2003 and May 2007 were retrospectively reviewed. Forty-four of the patients were male, and 10 were female. A mean age was 76 years old (range, 58-86 years old). Histology was squamous cell carcinoma in 22 patients, adenocarcinoma in 26, large cell carcinoma in 1, and non-small cell carcinoma in 5 patients. A median of follow-up duration was 20 months (range, 3-50 months). Treatment plans which were used in SBRT for the patients were recalculated with Eclipse (Varian) under the same monitor units under the following three conditions of heterogeneity correction: Batho power law correction (BPL), anisotropic analytical algorithm (AAA), and no heterogeneity correction (NC). Between patients who had local recurrence and patients with local lesion controlled, the following dose]volumetric data under each algorithm were compared: D95, minimal dose (Min) and mean dose of internal target volume (ITV) and planning target volume (PTV), and isocenter dose.