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Abstract # 2511 Dosimetric Predictors of Gastrostomy Tube Dependence at One Year in Patients with Squamous Cell Carcinoma of the Head and Neck

Presenter: Caudell, Jimmy

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Materials/Methods:
A database of 252 patients treated definitively with radiotherapy from 2001 ‐ 2006 at the University of Alabama‐Birmingham was queried. After excluding patients with a prior treatment for head and neck cancer, developed a local recurrence, had less than 12 months of follow‐up, were treated with conventional fields, or whose plans were unavailable, 67 patients remained for analysis. Concurrent chemotherapy was utilized in 54 of 67 (80.6%) of patients. Each patient’s soft palate, base of tongue, larynx (GSL), pharyngeal constrictors as one structure (PC), and separately as superior, middle, and inferior pharyngeal constrictors (IPC), and esophagus were contoured. Logistic regression was used to examine the relationship between the mean doses as well as V(d)s and the risk of PEG tube dependence at 12 months by swallowing structure. A stepwise logistic regression was performed to determine the most significant percentage dose variables.