The evaluated modified optical flow image registration shows promise in handling larger deformations of anatomical volumes as those due to respiration for lung cancer patients. This new modification enhances a classical multi‐resolution technique that is naturally incorporated in our fusion scheme. This is a unimodal non‐rigid registration that relies on the image intensity conservation. It can be applied to 2D, 3D and 4D images.
Author Disclosure: D. Michalski, None; M. Huq, None; D.E. Heron, None.